AHP Management
and Treatment Options

FIND AN APPROACH
FOR YOUR PATIENTS

AHP MANAGEMENT AND TREATMENT OPTIONS

Glucose and carbohydrate loading1,2

Used for the treatment of attacks

 

Hemin3,4

Used for the treatment of attacks

 

Hormone therapy (GnRH analogs)1,5

Used for patients experiencing AHP attacks related to their menstrual cycles

 

Liver transplantation3,5

Used rarely in severe cases where other approaches have been unsuccessful

 

Medications to treat pain1,6

Used to manage painful AHP symptoms

 

Medications to treat symptoms3

Used to treat and reduce AHP symptoms like nausea, constipation, tachycardia (fast heartbeat), and seizures

 

RNA interference therapy5

Used to help reduce the frequency of AHP attacks

 

Trigger avoidance5

Use caution with certain foods, drugs, and behaviors that may increase the risk of AHP attacks

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Treatment for Adults With AHP
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References: 1. Wang B, Rudnick S, Cengia B, Bonkovsky HL. Hepatol Commun. 2019;3(2):193-206. 2. Pischik E, Kauppinen R. Appl Clin Genet. 2015;8:201-214. 3. Anderson KE, Bloomer JR, Bonkovsky HL, et al. Ann lntern Med. 2005;142(6):439-450. 4. Panhematin [prescribing information]. Lebanon, NJ: Recordati Rare Diseases Inc; 2017. 5. Balwani M, Wang B, Anderson KE, et al; for the Porphyrias Consortium of Rare Diseases Clinical Research Network. Hepatology. 2017;66(4):1314-1322. 6. Puy H, Gouya L, Deybach JC. Lancet. 2010; 375:924-937.